Good hygienic performance Extruded composite heat-seal layer is produced under the GMP production environment, the molten LDPE is sprayed onto the substrate by the extruder after high-temperature heating, so that the hygienic performance of the product can be better ensured; while dry lamination or no The solvent compounded heat-sealed PE layer is blown or cast PE film, most of which are not produced in a GMP clean environment, and there is a greater risk in terms of hygienic performance.

At the same time, because the coating grade LDPE does not contain oxidants, slippery agents, etc., the use of coated LDPE as the heat-sealing layer is more hygienic than other materials in terms of migration and adsorption in terms of compatibility with drugs, so it is more suitable for drug packaging. . The thickness of each layer of the extrusion-coated composite film can be freely adjusted and controlled. The thickness of the dry composite film depends on the selected substrate and cannot be adjusted. Especially for the heat-sealing layer controlled below 30 μm, the blown film cannot be satisfied.

The thickness of the extruded composite extrusion layer can be set arbitrarily from 12 μm to 50 μm. Through online automatic thickness measurement, the thickness change of the product can be monitored in real time, and the thickness error range can be set through the man-machine interface. It can alarm in time, implement online automatic adjustment of die head gap adjustment on the man-machine interface in time, correct thickness error, accurately control thickness error, and print test data records to ensure stable product quality.

When producing composite films for pharmaceutical packaging, different heat-sealing resins should be selected according to different packaged objects, different packaging machines and different packaging conditions (temperature, speed, etc.). For pharmaceutical packaging with poor heat resistance, low-temperature heat-sealing materials should be used. For heavy-duty packaging, heat-sealing materials with high heat-sealing strength, high mechanical strength and good impact performance should be used. For high-speed packaging machines, low-temperature heat-sealing and heat-sealing materials with high hot-viscosity strength should be used. For pharmaceutical packaging with strong pollution such as powders and liquids, heat-sealing materials with excellent pollution resistance should be used.