Medical biodegradable materials not only need to have medical effects, but also need to be safe, non-toxic, non-irritating, and have excellent biocompatibility with the human body. Medical biodegradable materials mean that after completing medical functions, they can be dissolved and absorbed by dissolved enzymes in organisms. Biodegradable plastics have been widely used in surgical sutures, artificial skin, orthopedics, drug release agents in the body and absorbable sutures. lines and other fields.

1. Surgical sutures

An ideal suture has good adaptability in the body, is non-toxic, non-irritating, and can be absorbed by the tissue after maintaining a certain strength in the body. It can be absorbed by the tissue. Seaming performance, knotting and flexibility should meet the requirements of use. Raw sheep catgut is easy to produce antigenic body reaction and has adaptability to human body. Poor and not easy to store. Experiments have proved that medical sutures made of chitin and chitosan can be decomposed by lysozyme in the body and produce CO2 to be discharged

in vitro. The generated glycoprotein can be absorbed by the tissue, avoiding the trouble of removing stitches after surgery and reducing the pain of the patient. Urine, bile, and pancreatic juice all remained well. Strong, self-absorbing after use, does not cause allergies, and can also speed up wound healing.

2. Artificial skin

Human skin is a tissue with strong regenerative ability, but a large area of burns cannot be healed only by relying on one's own skin or autologous skin, and it needs artificial repair. During treatment, the skin acts as a temporary wound cover material to aid in healing. The function of artificial skin is: to prevent the evaporation and loss of water and body fluid in the wound; to prevent infection; to promote the growth of granulation or epithelium, and to promote treatment. artificial. At the same time, the skin can also be disinfected and sterilized to prevent bacterial infection, and it will not be harmful to the human body. A large number of artificial skins used commercially today are collagen carapaces. Enzymes catalyze biodegradation of materials, such as plain, poly-L-leucine.

3. Sustained-release drugs

After the tablet is taken orally and enters the human body, the concentration in the blood must reach a certain level to exert its physiological activity, that is, the blood concentration of the drug is too high. When the limit is set, side effects occur, and when the drug is metabolized by the body in the process of metabolism in the blood, the reduction of blood drug concentration does not work. The drug sustained-release agent made of biological detoxification polymer materials can maintain a constant release of drugs in the body for a long time, improve the therapeutic effect on high-risk patients such as cancer and heart disease, and make long-term antihypertensive treatment convenient and effective.

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